The active ingredient in the so-called essential phospholipids (EPL-substance) which are highly purified phosphatidylcholine fraction. Essential phospholipids in chemical structure similar to endogenous membrane phospholipids, which are greater in their functional properties due to the high content of polyunsaturated fatty acids, especially linoleic acid. Phospholipids are major structural components of cellular membranes and organel. They take part in the differentiation, division and cell regeneration. The functional significance of phospholipids based on their amphiphilic properties that allow you to adjust the permeability of cell membranes. They improve the properties of the membrane, in particular the ion exchange process of intracellular respiration, biological oxidation, affect the binding of intracellular enzymes respiration in mitochondria, as well as the process of oxidative phosphorylation in cell energy metabolism. Under physiological conditions, phospholipid synthesis satisfies the needs of normal hepatocytes, which contain a sufficient amount of phospholipids. It is known that the structure and function of the cell membrane enzyme systems for liver violated. Violated the biosynthesis of phospholipids, deficiency of which leads to dysfunction of the cell membrane. These processes are particularly pronounced in the mitochondria, which approximately 30% are composed of phospholipids which made the most important metabolic processes including oxidative phosphorylation. With a deficit of phospholipids is impaired fat metabolism, which leads to fatty degeneration of the liver. Due to its pharmacological properties Essenciale eliminates the violations, regeneration of cell membranes, membrane-bound enzyme reactivates the broken systems and receptors, increases the detoxification ability of the liver and thus normalizes its function.
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